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Synthesis and anticancer activity of thiosubstituted purines

New thiopurines with the propargylthio, pyrrolidinobutynylthio, sulfenamide, and sulfonamide groups in the pyrimidine ring were synthesized. The anticancer activity of these compounds and previously obtained 2- or 6-substituted azathioprine analogs and dialkylaminoalkylthiopurines were tested in vit...

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Detalles Bibliográficos
Autores principales: Kowalska, Alicja, Latocha, Małgorzata, Pluta, Krystian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491105/
https://www.ncbi.nlm.nih.gov/pubmed/26167104
http://dx.doi.org/10.1007/s00044-015-1364-2