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Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer

A large number of DNA copy number alterations (CNAs) exist in human breast cancers, and thus characterizing the most frequent CNAs is key to advancing therapeutics because it is likely that these regions contain breast tumor ‘drivers’ (i.e., cancer causal genes). This study aims to characterize the...

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Detalles Bibliográficos
Autores principales:	Silva, Grace O., He, Xiaping, Parker, Joel S., Gatza, Michael L., Carey, Lisa A., Hou, Jack P., Moulder, Stacy L., Marcom, Paul K., Ma, Jian, Rosen, Jeffrey M., Perou, Charles M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491106/ https://www.ncbi.nlm.nih.gov/pubmed/26109346 http://dx.doi.org/10.1007/s10549-015-3476-2

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