Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions

Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina...

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Autores principales: Anstead, Clare A., Korhonen, Pasi K., Young, Neil D., Hall, Ross S., Jex, Aaron R., Murali, Shwetha C., Hughes, Daniel S.T., Lee, Siu F., Perry, Trent, Stroehlein, Andreas J., Ansell, Brendan R.E., Breugelmans, Bert, Hofmann, Andreas, Qu, Jiaxin, Dugan, Shannon, Lee, Sandra L., Chao, Hsu, Dinh, Huyen, Han, Yi, Doddapaneni, Harsha V., Worley, Kim C., Muzny, Donna M., Ioannidis, Panagiotis, Waterhouse, Robert M., Zdobnov, Evgeny M., James, Peter J., Bagnall, Neil H., Kotze, Andrew C., Gibbs, Richard A., Richards, Stephen, Batterham, Philip, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491171/
https://www.ncbi.nlm.nih.gov/pubmed/26108605
http://dx.doi.org/10.1038/ncomms8344
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author Anstead, Clare A.
Korhonen, Pasi K.
Young, Neil D.
Hall, Ross S.
Jex, Aaron R.
Murali, Shwetha C.
Hughes, Daniel S.T.
Lee, Siu F.
Perry, Trent
Stroehlein, Andreas J.
Ansell, Brendan R.E.
Breugelmans, Bert
Hofmann, Andreas
Qu, Jiaxin
Dugan, Shannon
Lee, Sandra L.
Chao, Hsu
Dinh, Huyen
Han, Yi
Doddapaneni, Harsha V.
Worley, Kim C.
Muzny, Donna M.
Ioannidis, Panagiotis
Waterhouse, Robert M.
Zdobnov, Evgeny M.
James, Peter J.
Bagnall, Neil H.
Kotze, Andrew C.
Gibbs, Richard A.
Richards, Stephen
Batterham, Philip
Gasser, Robin B.
author_facet Anstead, Clare A.
Korhonen, Pasi K.
Young, Neil D.
Hall, Ross S.
Jex, Aaron R.
Murali, Shwetha C.
Hughes, Daniel S.T.
Lee, Siu F.
Perry, Trent
Stroehlein, Andreas J.
Ansell, Brendan R.E.
Breugelmans, Bert
Hofmann, Andreas
Qu, Jiaxin
Dugan, Shannon
Lee, Sandra L.
Chao, Hsu
Dinh, Huyen
Han, Yi
Doddapaneni, Harsha V.
Worley, Kim C.
Muzny, Donna M.
Ioannidis, Panagiotis
Waterhouse, Robert M.
Zdobnov, Evgeny M.
James, Peter J.
Bagnall, Neil H.
Kotze, Andrew C.
Gibbs, Richard A.
Richards, Stephen
Batterham, Philip
Gasser, Robin B.
author_sort Anstead, Clare A.
collection PubMed
description Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis.
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spelling pubmed-44911712015-07-08 Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions Anstead, Clare A. Korhonen, Pasi K. Young, Neil D. Hall, Ross S. Jex, Aaron R. Murali, Shwetha C. Hughes, Daniel S.T. Lee, Siu F. Perry, Trent Stroehlein, Andreas J. Ansell, Brendan R.E. Breugelmans, Bert Hofmann, Andreas Qu, Jiaxin Dugan, Shannon Lee, Sandra L. Chao, Hsu Dinh, Huyen Han, Yi Doddapaneni, Harsha V. Worley, Kim C. Muzny, Donna M. Ioannidis, Panagiotis Waterhouse, Robert M. Zdobnov, Evgeny M. James, Peter J. Bagnall, Neil H. Kotze, Andrew C. Gibbs, Richard A. Richards, Stephen Batterham, Philip Gasser, Robin B. Nat Commun Article Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis. Nature Pub. Group 2015-06-25 /pmc/articles/PMC4491171/ /pubmed/26108605 http://dx.doi.org/10.1038/ncomms8344 Text en Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Anstead, Clare A.
Korhonen, Pasi K.
Young, Neil D.
Hall, Ross S.
Jex, Aaron R.
Murali, Shwetha C.
Hughes, Daniel S.T.
Lee, Siu F.
Perry, Trent
Stroehlein, Andreas J.
Ansell, Brendan R.E.
Breugelmans, Bert
Hofmann, Andreas
Qu, Jiaxin
Dugan, Shannon
Lee, Sandra L.
Chao, Hsu
Dinh, Huyen
Han, Yi
Doddapaneni, Harsha V.
Worley, Kim C.
Muzny, Donna M.
Ioannidis, Panagiotis
Waterhouse, Robert M.
Zdobnov, Evgeny M.
James, Peter J.
Bagnall, Neil H.
Kotze, Andrew C.
Gibbs, Richard A.
Richards, Stephen
Batterham, Philip
Gasser, Robin B.
Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title_full Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title_fullStr Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title_full_unstemmed Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title_short Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
title_sort lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491171/
https://www.ncbi.nlm.nih.gov/pubmed/26108605
http://dx.doi.org/10.1038/ncomms8344
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