Variations of BRAF mutant allele percentage in melanomas

BACKGROUND: BRAF mutations are present in 40 % of human skin melanomas. Mutated tumors with an increased percentage of BRAF mutant alleles (BRAF-M%) may have a better response to RAF/MEK inhibitors. We evaluated the BRAF-M% in melanomas, and the genetic causes of its variation. METHODS: BRAF-M% was...

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Detalles Bibliográficos
Autores principales: Hélias-Rodzewicz, Zofia, Funck-Brentano, Elisa, Baudoux, Laure, Jung, Chan Kwon, Zimmermann, Ute, Marin, Cristi, Clerici, Thierry, Le Gall, Catherine, Peschaud, Frédérique, Taly, Valérie, Saiag, Philippe, Emile, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491198/
https://www.ncbi.nlm.nih.gov/pubmed/26141748
http://dx.doi.org/10.1186/s12885-015-1515-3

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