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Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains

BACKGROUND: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI–TcVI. CL Brener, the reference strain of the T. cruzi genome project, is a hybrid with a genome assembled into 41 putative chromosomes. Gene copy number variati...

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Detalles Bibliográficos
Autores principales: Reis-Cunha, João Luís, Rodrigues-Luiz, Gabriela F., Valdivia, Hugo O., Baptista, Rodrigo P., Mendes, Tiago A. O., de Morais, Guilherme Loss, Guedes, Rafael, Macedo, Andrea M., Bern, Caryn, Gilman, Robert H., Lopez, Carlos Talavera, Andersson, Björn, Vasconcelos, Ana Tereza, Bartholomeu, Daniella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491234/
https://www.ncbi.nlm.nih.gov/pubmed/26141959
http://dx.doi.org/10.1186/s12864-015-1680-4