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Accelerated extracellular matrix turnover during exacerbations of COPD
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) contribute significantly to disease progression. However, the effect on tissue structure and turnover is not well described. There is an urgent clinical need for biomarkers of disease activity associated with disease progressi...
Autores principales: | Sand, Jannie M. B., Knox, Alan J., Lange, Peter, Sun, Shu, Kristensen, Jacob H., Leeming, Diana J., Karsdal, Morten A., Bolton, Charlotte E., Johnson, Simon R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491243/ https://www.ncbi.nlm.nih.gov/pubmed/26062683 http://dx.doi.org/10.1186/s12931-015-0225-3 |
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