An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype

Several studies suggest that Wnt signaling contributes to reprogramming and maintenance of cancer stem cell (CSC) states activated by loss of membranous E-cadherin expression. However, E-cadherin's exact role in Wnt/β-catenin-mediated promotion of the CSC phenotype remains unclear. Recently, a...

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Detalles Bibliográficos
Autores principales: Su, Y-J, Chang, Y-W, Lin, W-H, Liang, C-L, Lee, J-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491612/
https://www.ncbi.nlm.nih.gov/pubmed/26075748
http://dx.doi.org/10.1038/oncsis.2015.17

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