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B cell-derived circulating granzyme B is a feature of acute infectious mononucleosis
Granzyme B (GzmB) is a serine protease best known for inducing target cell apoptosis when released by cytotoxic T lymphocytes (CTLs) or natural killer cells with pore-forming perforin. As a result, GzmB detected in the serum of virus-infected individuals has typically been attributed to these source...
Autores principales: | Hagn, Magdalena, Panikkar, Archana, Smith, Corey, Balfour Jr, Henry H, Khanna, Rajiv, Voskoboinik, Ilia, Trapani, Joseph A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491623/ https://www.ncbi.nlm.nih.gov/pubmed/26191409 http://dx.doi.org/10.1038/cti.2015.10 |
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