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Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression
We derived adult neural stem/progenitor cells (NSPCs) from the sub-ventricular zone of male and female mice to examine direct responses to principal sex hormones. In the presence of epidermal growth factor (EGF) and fibroblast growth factor-2 (FGF2) NSPCs of both sexes expressed nestin and sox2, and...
Autores principales: | Ransome, Mark I., Boon, Wah Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491627/ https://www.ncbi.nlm.nih.gov/pubmed/26217181 http://dx.doi.org/10.3389/fncel.2015.00253 |
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