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Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets

Glioblastoma (GBM), a WHO-defined Grade IV astrocytoma, is the most common and aggressive CNS malignancy. Despite current treatment modalities, the survival time remains dismal. The main cause of mortality in patients with this disease is reoccurrence of the malignancy, which is attributed to treatm...

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Detalles Bibliográficos
Autores principales: Jhanwar-Uniyal, Meena, Labagnara, Michael, Friedman, Marissa, Kwasnicki, Amanda, Murali, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491669/
https://www.ncbi.nlm.nih.gov/pubmed/25815458
http://dx.doi.org/10.3390/cancers7020538