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Emodin prevents intima thickness via Wnt4/Dvl-1/β-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery rats

Neointimal proliferation after vascular injury is a key mechanism of restenosis, a major cause of percutaneous transluminal angioplasty failure and artery bypass occlusion. Emodin, an anthraquinone with multiple physiological activities, has been reported to inhibit proliferation of vascular smooth...

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Detalles Bibliográficos
Autores principales: Hua, Jun-yi, He, Yu-zhou, Xu, Yun, Jiang, Xu-hong, Ye, Wu, Pan, Zhi-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491726/
https://www.ncbi.nlm.nih.gov/pubmed/26113441
http://dx.doi.org/10.1038/emm.2015.36