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Emodin prevents intima thickness via Wnt4/Dvl-1/β-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery rats
Neointimal proliferation after vascular injury is a key mechanism of restenosis, a major cause of percutaneous transluminal angioplasty failure and artery bypass occlusion. Emodin, an anthraquinone with multiple physiological activities, has been reported to inhibit proliferation of vascular smooth...
Autores principales: | Hua, Jun-yi, He, Yu-zhou, Xu, Yun, Jiang, Xu-hong, Ye, Wu, Pan, Zhi-min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491726/ https://www.ncbi.nlm.nih.gov/pubmed/26113441 http://dx.doi.org/10.1038/emm.2015.36 |
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