Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression

Low pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour site, while sparing healthy tissues. To this end, pH-sensitive, hollow ZnO-nanocarriers loaded with...

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Detalles Bibliográficos
Autores principales: Puvvada, Nagaprasad, Rajput, Shashi, Kumar, B.N. Prashanth, Sarkar, Siddik, Konar, Suraj, Brunt, Keith R., Rao, Raj R., Mazumdar, Abhijit, Das, Swadesh K., Basu, Ranadhir, Fisher, Paul B., Mandal, Mahitosh, Pathak, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491843/
https://www.ncbi.nlm.nih.gov/pubmed/26145450
http://dx.doi.org/10.1038/srep11760

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