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Diet-induced obesity impairs hypothalamic glucose sensing but not glucose hypothalamic extracellular levels, as measured by microdialysis
BACKGROUND/OBJECTIVES: Glucose from the diet may signal metabolic status to hypothalamic sites controlling energy homeostasis. Disruption of this mechanism may contribute to obesity but its relevance has not been established. The present experiments aimed at evaluating whether obesity induced by chr...
Autores principales: | de Andrade, I S, Zemdegs, J C S, de Souza, A P, Watanabe, R L H, Telles, M M, Nascimento, C M O, Oyama, L M, Ribeiro, E B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491853/ https://www.ncbi.nlm.nih.gov/pubmed/26075639 http://dx.doi.org/10.1038/nutd.2015.12 |
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