DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

BACKGROUND: Although the etiology of primary biliary cirrhosis (PBC) remains enigmatic, there are several pieces of data supporting the thesis that a strong genetic predisposition and environmental factors interact to produce a selective loss of tolerance. The striking female predominance of PBC has...

Descripción completa

Detalles Bibliográficos
Autores principales: Lleo, Ana, Zhang, Weici, Zhao, Ming, Tan, Yixin, Bernuzzi, Francesca, Zhu, Bochen, Liu, Qian, Tan, Qiqun, Malinverno, Federica, Valenti, Luca, Jiang, Tingting, Tan, Lina, Liao, Wei, Coppel, Ross, Invernizzi, Pietro, Lu, Qianjin, Adams, David H., Gershwin, M. Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491885/
https://www.ncbi.nlm.nih.gov/pubmed/26150899
http://dx.doi.org/10.1186/s13148-015-0098-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491885/
https://www.ncbi.nlm.nih.gov/pubmed/26150899
http://dx.doi.org/10.1186/s13148-015-0098-9

Ejemplares similares