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STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE

BACKGROUND: In experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, mice genetically deficient in the transcription factor signal transducer and activator of transcription 4 (STAT4) are resistant to disease. In contrast, deletion or inhibition of the Th1-associated c...

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Detalles Bibliográficos
Autores principales:	McWilliams, Ian L., Rajbhandari, Rajani, Nozell, Susan, Benveniste, Etty, Harrington, Laurie E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491892/ https://www.ncbi.nlm.nih.gov/pubmed/26123499 http://dx.doi.org/10.1186/s12974-015-0351-3

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