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Ultra-large alignments using phylogeny-aware profiles

Many biological questions, including the estimation of deep evolutionary histories and the detection of remote homology between protein sequences, rely upon multiple sequence alignments and phylogenetic trees of large datasets. However, accurate large-scale multiple sequence alignment is very diffic...

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Detalles Bibliográficos
Autores principales: Nguyen, Nam-phuong D., Mirarab, Siavash, Kumar, Keerthana, Warnow, Tandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492008/
https://www.ncbi.nlm.nih.gov/pubmed/26076734
http://dx.doi.org/10.1186/s13059-015-0688-z

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