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The unifrac significance test is sensitive to tree topology

Long et al. (BMC Bioinformatics 2014, 15(1):278) describe a “discrepancy” in using UniFrac to assess statistical significance of community differences. Specifically, they find that weighted UniFrac results differ between input trees where (a) replicate sequences each have their own tip, or (b) all r...

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Detalles Bibliográficos
Autores principales: Lozupone, Catherine A., Knight, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492014/
https://www.ncbi.nlm.nih.gov/pubmed/26150095
http://dx.doi.org/10.1186/s12859-015-0640-y