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Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress

Lipotoxicity plays an important role in pancreatic β-cell failure during the development of type 2 diabetes. Prolonged exposure of β-cells to elevated free fatty acids level could cause deterioration of β-cell function and induce cell apoptosis. Therefore, inhibition of fatty acids-induced β-cell dy...

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Detalles Bibliográficos
Autores principales:	Zhou, Yuren, Sun, Peng, Wang, Ting, Chen, Kaixian, Zhu, Weiliang, Wang, Heyao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492560/ https://www.ncbi.nlm.nih.gov/pubmed/26147439 http://dx.doi.org/10.1371/journal.pone.0132411

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