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Ad35.CS.01 - RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults
METHODS: In an observer blind, phase 2 trial, 55 adults were randomized to receive one dose of Ad35.CS.01 vaccine followed by two doses of RTS,S/AS01 (ARR-group) or three doses of RTS,S/AS01 (RRR-group) at months 0, 1, 2 followed by controlled human malaria infection. RESULTS: ARR and RRR vaccine re...
Autores principales: | Ockenhouse, Christian F., Regules, Jason, Tosh, Donna, Cowden, Jessica, Kathcart, April, Cummings, James, Paolino, Kristopher, Moon, James, Komisar, Jack, Kamau, Edwin, Oliver, Thomas, Chhoeu, Austin, Murphy, Jitta, Lyke, Kirsten, Laurens, Matthew, Birkett, Ashley, Lee, Cynthia, Weltzin, Rich, Wille-Reece, Ulrike, Sedegah, Martha, Hendriks, Jenny, Versteege, Isabella, Pau, Maria Grazia, Sadoff, Jerold, Vanloubbeeck, Yannick, Lievens, Marc, Heerwegh, Dirk, Moris, Philippe, Guerra Mendoza, Yolanda, Jongert, Erik, Cohen, Joe, Voss, Gerald, Ballou, W. Ripley, Vekemans, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492580/ https://www.ncbi.nlm.nih.gov/pubmed/26148007 http://dx.doi.org/10.1371/journal.pone.0131571 |
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