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Leber hereditary optic neuropathy: current perspectives

Leber hereditary optic neuropathy (LHON) is one of the most common inherited optic neuropathies causing bilateral central vision loss. The disorder results from point mutations in mitochondrial DNA and subsequent mitochondrial dysfunction. The primary cell type that is lost in LHON is the retinal ga...

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Detalles Bibliográficos
Autores principales: Meyerson, Cherise, Van Stavern, Greg, McClelland, Collin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492634/
https://www.ncbi.nlm.nih.gov/pubmed/26170609
http://dx.doi.org/10.2147/OPTH.S62021