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Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment
BACKGROUND: The self-renewing ability of HSCs is fundamental for the maintenance of a pool of bone marrow precursors throughout the life of an individual. The genetic mechanisms underlying such a complex process are still poorly understood. RESULTS AND SIGNIFICANCE: Here, we show that constitutive i...
Autores principales: | Kauffman, Lauren, Balatti, Veronica, Cascione, Luciano, Fadda, Paolo, Racke, Frederick, Santhanam, Ramasamy, Costinean, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492741/ https://www.ncbi.nlm.nih.gov/pubmed/26147501 http://dx.doi.org/10.1371/journal.pone.0131981 |
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