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Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

OBJECTIVES: Precursor Th17 lineage cells expressing CD161 are implicated in Rheumatoid Arthritis (RA) pathogenesis. CD4+CD161+ T-cells accumulate in RA joints and may acquire a non classical Th1 phenotype. The endogenous ligand for CD161 is lectin-like transcript 1 (LLT1). CD161/LLT1 ligation may co...

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Detalles Bibliográficos
Autores principales:	Chalan, Paulina, Bijzet, Johan, Huitema, Minke G., Kroesen, Bart-Jan, Brouwer, Elisabeth, Boots, Annemieke M. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492745/ https://www.ncbi.nlm.nih.gov/pubmed/26147876 http://dx.doi.org/10.1371/journal.pone.0132436

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