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The discovery of a selective and potent A(2a) agonist with extended lung retention

Although the anti-inflammatory role of the A(2a) receptor is well established, controversy remains with regard to the therapeutic value for A(2a) agonists in treatment of inflammatory lung diseases, also as a result of unwanted A(2a)-mediated cardiovascular effects. In this paper, we describe the di...

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Detalles Bibliográficos
Autores principales: Åstrand, Annika B M, Lamm Bergström, Eva, Zhang, Hui, Börjesson, Lena, Söderdahl, Therese, Wingren, Cecilia, Jansson, Anne-Helene, Smailagic, Amir, Johansson, Camilla, Bladh, Håkan, Shamovsky, Igor, Tunek, Anders, Drmota, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492750/
https://www.ncbi.nlm.nih.gov/pubmed/26236482
http://dx.doi.org/10.1002/prp2.134