DSP-1053, a novel serotonin reuptake inhibitor with 5-HT(1A) partial agonistic activity, displays fast antidepressant effect with minimal undesirable effects in juvenile rats

Enhancement of serotonergic neurotransmission has been the main stream of treatment for patients with depression. However, delayed therapeutic onset and undesirable side effects are major drawbacks for conventional serotonin reuptake inhibitors. Here, we show that DSP-1053, a novel serotonin reuptak...

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Detalles Bibliográficos
Autores principales: Kato, Taro, Matsumoto, Yuji, Yamamoto, Masanori, Matsumoto, Kenji, Baba, Satoko, Nakamichi, Keiko, Matsuda, Harumi, Nishimuta, Haruka, Yabuuchi, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492758/
https://www.ncbi.nlm.nih.gov/pubmed/26171224
http://dx.doi.org/10.1002/prp2.142

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