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Sulfonamide inhibitors of α2β1 integrin reveal the essential role of collagen receptors in in vivo models of inflammation
Small molecule inhibitors of α2β1 integrin, a major cellular collagen receptor, have been reported to inhibit platelet function, kidney injury, and angiogenesis. Since α2β1 integrin is abundantly expressed on various inflammation-associated cells, we tested whether recently developed α2β1 blocking s...
Autores principales: | Nissinen, Liisa, Ojala, Marika, Langen, Barbara, Dost, Rita, Pihlavisto, Marjo, Käpylä, Jarmo, Marjamäki, Anne, Heino, Jyrki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492762/ https://www.ncbi.nlm.nih.gov/pubmed/26171226 http://dx.doi.org/10.1002/prp2.146 |
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