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Dimeric human sulfotransferase 1B1 displays cofactor-dependent subunit communication

The cytosolic sulfotransferases (SULTs) are dimeric enzymes that catalyze the transformation of hydrophobic drugs and hormones into hydrophilic sulfate esters thereby providing the body with an important pathway for regulating small molecule activity and excretion. While SULT dimerization is highly...

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Detalles Bibliográficos
Autores principales: Tibbs, Zachary E, Falany, Charles N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492763/
https://www.ncbi.nlm.nih.gov/pubmed/26236487
http://dx.doi.org/10.1002/prp2.147