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Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells
There has been intensive effort to identify in vivo biomarkers that can be used to monitor drug-induced kidney damage and identify injury before significant impairment occurs. Kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), and human macrophage colony stimulating...
Autores principales: | Huang, Johnny X, Kaeslin, Geraldine, Ranall, Max V, Blaskovich, Mark A, Becker, Bernd, Butler, Mark S, Little, Melissa H, Lash, Lawrence H, Cooper, Matthew A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492764/ https://www.ncbi.nlm.nih.gov/pubmed/26171227 http://dx.doi.org/10.1002/prp2.148 |
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