Cargando…

Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2

Exposure of biological membranes to reactive oxygen species creates a complex mixture of distinct oxidized phospholipid (OxPL) species, which contribute to the development of chronic inflammatory diseases and metabolic disorders. While the ability of OxPL to modulate biological processes is increasi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bretscher, Peter, Egger, Julian, Shamshiev, Abdijapar, Trötzmüller, Martin, Köfeler, Harald, Carreira, Erick M, Kopf, Manfred, Freigang, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492819/ https://www.ncbi.nlm.nih.gov/pubmed/25770125 http://dx.doi.org/10.15252/emmm.201404702

Ejemplares similares

Dyslipidemia inhibits Toll-like receptor–induced activation of CD8α-negative dendritic cells and protective Th1 type immunity
por: Shamshiev, Abdijapar T., et al.
Publicado: (2007)

Lipidomics from sample preparation to data analysis: a primer
por: Züllig, Thomas, et al.
Publicado: (2019)

Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose
por: Muri, Jonathan, et al.
Publicado: (2020)

Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor–γ/δ Stimulated by Nonpeptidic Ligands
por: Carena, Ilaria, et al.
Publicado: (1997)

Mass Spectrometry Based Lipidomics: An Overview of Technological Platforms
por: Köfeler, Harald C., et al.
Publicado: (2012)

Quantitative analysis of N‐acylphosphatidylethanolamine molecular species in rat brain using solid‐phase extraction combined with reversed‐phase chromatography and tandem mass spectrometry
por: Triebl, Alexander, et al.
Publicado: (2016)

Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid
por: Miek, Laura, et al.
Publicado: (2022)

Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids
por: Artru, Florent, et al.
Publicado: (2022)

Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis
por: Piattini, Federica, et al.
Publicado: (2021)

Assessment of lipidomic species in hepatocyte lipid droplets from stressed mouse models
por: Hartler, Jürgen, et al.
Publicado: (2014)

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells
por: Leithner, Katharina, et al.
Publicado: (2018)

A Metabolomics Workflow for Analyzing Complex Biological Samples Using a Combined Method of Untargeted and Target-List Based Approaches
por: Züllig, Thomas, et al.
Publicado: (2020)

The association of eicosanoids and eicosanoid-related metabolites with pulmonary hypertension
por: McNeill, Jenna N., et al.
Publicado: (2023)

Automated Annotation of Sphingolipids Including Accurate Identification of Hydroxylation Sites Using MS(n) Data
por: Hartler, Jürgen, et al.
Publicado: (2020)

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
por: Thomas, Christopher P., et al.
Publicado: (2010)

Changes in Phospholipid/Ceramide Profiles and Eicosanoid Levels in the Plasma of Rats Irradiated with UV Rays and Treated Topically with Cannabidiol
por: Łuczaj, Wojciech, et al.
Publicado: (2021)

Eicosanoids in reproduction /
Publicado: (1990)

Eicosanoids and cancer
por: Gomes, Renata Nascimento, et al.
Publicado: (2018)

Lipid Mediators Are Critical in Resolving Inflammation: A Review of the Emerging Roles of Eicosanoids in Diabetes Mellitus
por: Tessaro, Fernando H. G., et al.
Publicado: (2015)

DLX1008 (brolucizumab), a single-chain anti-VEGF-A antibody fragment with low picomolar affinity, leads to tumor involution in an in vivo model of Kaposi Sarcoma
por: Eason, Anthony B., et al.
Publicado: (2020)

Sequestration of polyunsaturated fatty acids in membrane phospholipids of Caenorhabditis elegans dauer larva attenuates eicosanoid biosynthesis for prolonged survival
por: Lam, Sin Man, et al.
Publicado: (2017)

Editorial: Eicosanoids in Cancer
por: Markosyan, Nune, et al.
Publicado: (2021)

Isomer-Resolved Mass Spectrometry Imaging of Acidic Phospholipids
por: Claes, Britt S. R., et al.
Publicado: (2023)

Human Milk Oligosaccharides Are Present in Amniotic Fluid and Show Specific Patterns Dependent on Gestational Age
por: Jantscher-Krenn, Evelyn, et al.
Publicado: (2022)

Tear eicosanoids in healthy people and ocular surface disease
por: Ambaw, Yohannes Abere, et al.
Publicado: (2018)

Determination of Oxidized Phosphatidylcholines by Hydrophilic Interaction Liquid Chromatography Coupled to Fourier Transform Mass Spectrometry
por: Sala, Pia, et al.
Publicado: (2015)

Phospholipid dynamics in ex vivo lung cancer and normal lung explants
por: Lesko, Julia, et al.
Publicado: (2021)

Eicosanoids in Nonalcoholic Fatty Liver Disease (NAFLD) Progression. Do Serum Eicosanoids Profile Correspond with Liver Eicosanoids Content during NAFLD Development and Progression?
por: Maciejewska, Dominika, et al.
Publicado: (2020)

Regulation of eicosanoid synthesis by leptin
por: Mancuso, P, et al.
Publicado: (2004)

Eicosanoid Diversity of Stony Corals
por: Lõhelaid, Helike, et al.
Publicado: (2018)

The Role of Eicosanoids in Alzheimer’s Disease
por: Biringer, Roger G.
Publicado: (2019)

The Role of Eicosanoids in Gynecological Malignancies
por: Smith, Paige G., et al.
Publicado: (2020)

Eicosanoids in Skin Wound Healing
por: Yasukawa, Ken, et al.
Publicado: (2020)

Eicosanoids: Atherosclerosis and cardiometabolic health
por: Piper, Kimberly, et al.
Publicado: (2020)

Eicosanoids in inflammation in the blood and the vessel
por: Yamaguchi, Adriana, et al.
Publicado: (2022)

Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice
por: Schiffrin, Mariano, et al.
Publicado: (2021)

Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin
por: Crescente, Marilena, et al.
Publicado: (2020)

Potent Anti‐Inflammatory and Pro‐Resolving Effects of Anabasum in a Human Model of Self‐Resolving Acute Inflammation
por: Motwani, Madhur P., et al.
Publicado: (2018)

Eicosanoid and eicosanoid-related inflammatory mediators and exercise intolerance in heart failure with preserved ejection fraction
por: Lau, Emily S., et al.
Publicado: (2023)

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
por: Dimas, Penelope, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8enld2ljt09pbckpp7ijlduoqo