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Novel Associations between FAAH Genetic Variants and Postoperative Central Opioid related Adverse Effects
Opioid effects are potentiated by cannabinoid agonists including anandamide, an endocannabinoid. Inter-individual variability in responses to opioids is a major clinical problem. Multiple deaths and anoxic brain injuries occur every year in due to opioid induced respiratory depression in surgical pa...
Autores principales: | Sadhasivam, Senthilkumar, Zhang, Xue, Chidambaran, Vidya, Mavi, Jagroop, Pilipenko, Valentina, Mersha, Tesfaye B., Meller, Jaroslaw, Kaufman, Kenneth M., Martin, Lisa J., McAuliffe, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492912/ https://www.ncbi.nlm.nih.gov/pubmed/25558980 http://dx.doi.org/10.1038/tpj.2014.79 |
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