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14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia

The down-modulation of the β-catenin antagonist Chibby 1 (CBY1) associated with the BCR-ABL1 fusion gene of chronic myeloid leukemia (CML) contributes to the aberrant activation of β-catenin, particularly in leukemic stem cells (LSC) resistant to tyrosine kinase (TK) inhibitors. It is, at least part...

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Detalles Bibliográficos
Autores principales:	Mancini, Manuela, Leo, Elisa, Takemaru, Ken-Ichi, Campi, Virginia, Castagnetti, Fausto, Soverini, Simona, De Benedittis, Caterina, Rosti, Gianantonio, Cavo, Michele, Santucci, Maria Alessandra, Martinelli, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492953/ https://www.ncbi.nlm.nih.gov/pubmed/26147002 http://dx.doi.org/10.1371/journal.pone.0131074

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