Cargando…
Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage
Environmental and metabolic sources of reactive oxygen species (ROS) can damage DNA, proteins and lipids to promote disease. Regulation of gene expression can prevent this damage and can include increased transcription, translation and post translational modification. Cellular responses to ROS play...
Autores principales: | Endres, Lauren, Begley, Ulrike, Clark, Ryan, Gu, Chen, Dziergowska, Agnieszka, Małkiewicz, Andrzej, Melendez, J. Andres, Dedon, Peter C., Begley, Thomas J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492958/ https://www.ncbi.nlm.nih.gov/pubmed/26147969 http://dx.doi.org/10.1371/journal.pone.0131335 |
Ejemplares similares
-
The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene
por: Leonardi, Andrea, et al.
Publicado: (2020) -
Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming
por: Lee, May Y., et al.
Publicado: (2019) -
tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence
por: Chionh, Yok Hian, et al.
Publicado: (2016) -
Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression
por: Gu, Chen, et al.
Publicado: (2018) -
Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome
por: Huber, Sabrina M., et al.
Publicado: (2022)