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Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture

In renal collecting duct (CD) principal cells (PCs), vasopressin (VP) acts through its receptor, V2R, to increase intracellular cAMP leading to phosphorylation and apical membrane accumulation of the water channel aquaporin 2 (AQP2). The trafficking and function of basolaterally located AQP2 is, how...

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Detalles Bibliográficos
Autores principales:	Rice, William L., Li, Wei, Mamuya, Fahmy, McKee, Mary, Păunescu, Teodor G., Lu, Hua A. Jenny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493001/ https://www.ncbi.nlm.nih.gov/pubmed/26147297 http://dx.doi.org/10.1371/journal.pone.0131719

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