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Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets

BACKGROUND AND METHODS: Highly pathogenic avian influenza (HPAI) viruses constitute a pandemic threat and the development of effective vaccines is a global priority. Sixty adults were recruited into a randomized clinical trial and were intramuscularly immunized with two virosomal vaccine H5N1 (NIBRG...

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Detalles Bibliográficos
Autores principales:	Cox, Rebecca J., Major, Diane, Pedersen, Gabriel, Pathirana, Rishi D., Hoschler, Katja, Guilfoyle, Kate, Roseby, Sarah, Bredholt, Geir, Assmus, Jörg, Breakwell, Lucy, Campitelli, Laura, Sjursen, Haakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493055/ https://www.ncbi.nlm.nih.gov/pubmed/26147369 http://dx.doi.org/10.1371/journal.pone.0131652

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