A highlight from the LUPUS 2014 meeting: eight great ideas

This review describes eight ‘great ideas’ regarding bench-to-bedside considerations in systemic lupus erythematosus (SLE) presented at the second international LUPUS meeting in Quebec, September 2014. The topics included: correcting the impaired clearance of apoptotic fragments; optimisation of clin...

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Autores principales: Buyon, Jill P, Cohen, Phillip, Merrill, Joan T, Gilkeson, Gary, Kaplan, Mariana, James, Judith, McCune, W Joseph, Bernatsky, Sasha, Elkon, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493165/
https://www.ncbi.nlm.nih.gov/pubmed/26167290
http://dx.doi.org/10.1136/lupus-2015-000087
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author Buyon, Jill P
Cohen, Phillip
Merrill, Joan T
Gilkeson, Gary
Kaplan, Mariana
James, Judith
McCune, W Joseph
Bernatsky, Sasha
Elkon, Keith
author_facet Buyon, Jill P
Cohen, Phillip
Merrill, Joan T
Gilkeson, Gary
Kaplan, Mariana
James, Judith
McCune, W Joseph
Bernatsky, Sasha
Elkon, Keith
author_sort Buyon, Jill P
collection PubMed
description This review describes eight ‘great ideas’ regarding bench-to-bedside considerations in systemic lupus erythematosus (SLE) presented at the second international LUPUS meeting in Quebec, September 2014. The topics included: correcting the impaired clearance of apoptotic fragments; optimisation of clinical trial design: the PERFECT (Pre Evaluation Reducing Frighteningly Elevated Coverable Targets) study; lipidomics and metabolomics in SLE; importance of the inflammasome; identification and treatment of asymptomatic autoimmunity: prevention of SLE; combining low doses of hydroxychloroquine and quinacrine for long-term maintenance therapy of SLE; reducing emergency room visits and the critical relevance of the autoantigen.
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spelling pubmed-44931652015-07-10 A highlight from the LUPUS 2014 meeting: eight great ideas Buyon, Jill P Cohen, Phillip Merrill, Joan T Gilkeson, Gary Kaplan, Mariana James, Judith McCune, W Joseph Bernatsky, Sasha Elkon, Keith Lupus Sci Med Review This review describes eight ‘great ideas’ regarding bench-to-bedside considerations in systemic lupus erythematosus (SLE) presented at the second international LUPUS meeting in Quebec, September 2014. The topics included: correcting the impaired clearance of apoptotic fragments; optimisation of clinical trial design: the PERFECT (Pre Evaluation Reducing Frighteningly Elevated Coverable Targets) study; lipidomics and metabolomics in SLE; importance of the inflammasome; identification and treatment of asymptomatic autoimmunity: prevention of SLE; combining low doses of hydroxychloroquine and quinacrine for long-term maintenance therapy of SLE; reducing emergency room visits and the critical relevance of the autoantigen. BMJ Publishing Group 2015-06-30 /pmc/articles/PMC4493165/ /pubmed/26167290 http://dx.doi.org/10.1136/lupus-2015-000087 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Review
Buyon, Jill P
Cohen, Phillip
Merrill, Joan T
Gilkeson, Gary
Kaplan, Mariana
James, Judith
McCune, W Joseph
Bernatsky, Sasha
Elkon, Keith
A highlight from the LUPUS 2014 meeting: eight great ideas
title A highlight from the LUPUS 2014 meeting: eight great ideas
title_full A highlight from the LUPUS 2014 meeting: eight great ideas
title_fullStr A highlight from the LUPUS 2014 meeting: eight great ideas
title_full_unstemmed A highlight from the LUPUS 2014 meeting: eight great ideas
title_short A highlight from the LUPUS 2014 meeting: eight great ideas
title_sort highlight from the lupus 2014 meeting: eight great ideas
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493165/
https://www.ncbi.nlm.nih.gov/pubmed/26167290
http://dx.doi.org/10.1136/lupus-2015-000087
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