Role of the IL-6 Gene in the Etiopathogenesis of Idiopathic Scoliosis

Scoliotic human nuclei pulposi can respond to exogenous proinflammatory stimuli by secreting increased amounts of interleukin-6 (IL-6). The G/C polymorphism of the promoter region of IL-6 gene influences levels and functional activity of the IL-6 protein. We conducted a case-control study of eighty...

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Detalles Bibliográficos
Autores principales: Nikolova, Svetla, Dikova, Milka, Dikov, Dobrin, Djerov, Assen, Dzhebir, Gyulnas, Atanasov, Ventseslav, Savov, Alexey, Kremensky, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493265/
https://www.ncbi.nlm.nih.gov/pubmed/26199858
http://dx.doi.org/10.1155/2015/621893

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