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Prevalence of Hepatitis E Virus among Adults in South-West of Iran

Background. Knowledge regarding prevalence of HEV in general population can be an indicator of the public health and hygiene. Therefore, this study was conducted to evaluate the prevalence of HEV among adults in South-West of Iran. Methods. Blood samples were taken from 510 participants, 206 (40.4%)...

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Autores principales: Farshadpour, Fatemeh, Taherkhani, Reza, Makvandi, Manoochehr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493289/
https://www.ncbi.nlm.nih.gov/pubmed/26199756
http://dx.doi.org/10.1155/2015/759589
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author Farshadpour, Fatemeh
Taherkhani, Reza
Makvandi, Manoochehr
author_facet Farshadpour, Fatemeh
Taherkhani, Reza
Makvandi, Manoochehr
author_sort Farshadpour, Fatemeh
collection PubMed
description Background. Knowledge regarding prevalence of HEV in general population can be an indicator of the public health and hygiene. Therefore, this study was conducted to evaluate the prevalence of HEV among adults in South-West of Iran. Methods. Blood samples were taken from 510 participants, 206 (40.4%) males and 304 (59.6%) females from February to July 2014. Detection of anti-HEV IgG and IgM antibodies was carried out by ELISA test. Results. The overall anti-HEV IgG and IgM prevalence rates were 46.1% and 1.4%, respectively. Anti-HEV IgG and IgM seropositivity were not statistically associated with gender and race/ethnicity. Meanwhile, there were significant differences between the age groups regarding HEV IgG and IgM seropositivity. HEV IgG seroprevalence increased with age from 14.3% in subjects aged 18–30 years to 71.4% in persons over 71 years old, and considerably individuals aged 61 to 70 years had the highest HEV prevalence (90.9%). Also, 5.7% in the age group 18–30 years and 2.2% in the age group 31–40 years were positive for anti-HEV IgM antibodies and the highest rate was observed in subjects aged 18–30 years. Conclusion. In conclusion, high HEV IgG seroprevalence of 46.1% was observed among adults in South-West of Iran.
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spelling pubmed-44932892015-07-21 Prevalence of Hepatitis E Virus among Adults in South-West of Iran Farshadpour, Fatemeh Taherkhani, Reza Makvandi, Manoochehr Hepat Res Treat Research Article Background. Knowledge regarding prevalence of HEV in general population can be an indicator of the public health and hygiene. Therefore, this study was conducted to evaluate the prevalence of HEV among adults in South-West of Iran. Methods. Blood samples were taken from 510 participants, 206 (40.4%) males and 304 (59.6%) females from February to July 2014. Detection of anti-HEV IgG and IgM antibodies was carried out by ELISA test. Results. The overall anti-HEV IgG and IgM prevalence rates were 46.1% and 1.4%, respectively. Anti-HEV IgG and IgM seropositivity were not statistically associated with gender and race/ethnicity. Meanwhile, there were significant differences between the age groups regarding HEV IgG and IgM seropositivity. HEV IgG seroprevalence increased with age from 14.3% in subjects aged 18–30 years to 71.4% in persons over 71 years old, and considerably individuals aged 61 to 70 years had the highest HEV prevalence (90.9%). Also, 5.7% in the age group 18–30 years and 2.2% in the age group 31–40 years were positive for anti-HEV IgM antibodies and the highest rate was observed in subjects aged 18–30 years. Conclusion. In conclusion, high HEV IgG seroprevalence of 46.1% was observed among adults in South-West of Iran. Hindawi Publishing Corporation 2015 2015-06-23 /pmc/articles/PMC4493289/ /pubmed/26199756 http://dx.doi.org/10.1155/2015/759589 Text en Copyright © 2015 Fatemeh Farshadpour et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Farshadpour, Fatemeh
Taherkhani, Reza
Makvandi, Manoochehr
Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title_full Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title_fullStr Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title_full_unstemmed Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title_short Prevalence of Hepatitis E Virus among Adults in South-West of Iran
title_sort prevalence of hepatitis e virus among adults in south-west of iran
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493289/
https://www.ncbi.nlm.nih.gov/pubmed/26199756
http://dx.doi.org/10.1155/2015/759589
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