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Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding

The aim of this study is to determine the mechanism of sepsis-induced vascular hyperpermeability and the beneficial effect of glucocorticoid in protecting vascular endothelium. Male Sprague-Dawley rats were given either a bolus intraperitoneal injection of a nonlethal dose of LPS (Escherichia coli 0...

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Detalles Bibliográficos
Autores principales: Cui, Na, Wang, Hao, Long, Yun, Su, Longxiang, Liu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493300/
https://www.ncbi.nlm.nih.gov/pubmed/26199464
http://dx.doi.org/10.1155/2015/912726

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