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Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation

Interleukin- (IL-) 17A, a pleiotropic mediator of inflammation and autoimmunity, potently stimulates bone-marrow neutrophil production. To explore IL-17A effects on eosinopoiesis, we cultured bone-marrow from wild-type mice, or mutants lacking inducible nitric oxide synthase (iNOS−/−), CD95 (lpr), I...

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Detalles Bibliográficos
Autores principales: Xavier-Elsas, Pedro, de Luca, Bianca, Queto, Túlio, Vieira, Bruno Marques, Masid-de-Brito, Daniela, Dahab, Elizabeth Chen, Alves Filho, José Carlos, Cunha, Fernando Q., Gaspar-Elsas, Maria Ignez C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493302/
https://www.ncbi.nlm.nih.gov/pubmed/26199466
http://dx.doi.org/10.1155/2015/968932