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Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers
Studies on the biology of mucosal-associated invariant T cells (MAIT cells) in mice have been hampered by a lack of specific reagents. Using MR1-antigen (Ag) tetramers that specifically bind to the MR1-restricted MAIT T cell receptors (TCRs), we demonstrate that MAIT cells are detectable in a broad...
Autores principales: | Rahimpour, Azad, Koay, Hui Fern, Enders, Anselm, Clanchy, Rhiannon, Eckle, Sidonia B.G., Meehan, Bronwyn, Chen, Zhenjun, Whittle, Belinda, Liu, Ligong, Fairlie, David P., Goodnow, Chris C., McCluskey, James, Rossjohn, Jamie, Uldrich, Adam P., Pellicci, Daniel G., Godfrey, Dale I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493408/ https://www.ncbi.nlm.nih.gov/pubmed/26101265 http://dx.doi.org/10.1084/jem.20142110 |
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