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The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function

Regulatory T cell (T reg cell) numbers and activities are tightly calibrated to maintain immune homeostasis, but the mechanisms involved are incompletely defined. Here, we report that the lysophosphatidylserine (LysoPS) receptor GPR174 is abundantly expressed in developing and mature T reg cells. In...

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Detalles Bibliográficos
Autores principales:	Barnes, Michael J., Li, Chien-Ming, Xu, Ying, An, Jinping, Huang, Yong, Cyster, Jason G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493414/ https://www.ncbi.nlm.nih.gov/pubmed/26077720 http://dx.doi.org/10.1084/jem.20141827

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