Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness

The goal of this study was to investigate how alterations in extracellular matrix (ECM) biophysical properties modulate corneal keratocyte phenotypes in response to specific wound healing cytokines and Rho GTPases. Rabbit corneal keratocytes were plated within standard collagen matrices (2.5 mg/mL)...

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Detalles Bibliográficos
Autores principales: Petroll, W. Matthew, Lakshman, Neema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493509/
https://www.ncbi.nlm.nih.gov/pubmed/25874856
http://dx.doi.org/10.3390/jfb6020222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493509/
https://www.ncbi.nlm.nih.gov/pubmed/25874856
http://dx.doi.org/10.3390/jfb6020222

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