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Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493545/ https://www.ncbi.nlm.nih.gov/pubmed/25871832 http://dx.doi.org/10.3390/bios5020187 |
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author | Gartmann, Thomas E. Kehl, Florian |
author_facet | Gartmann, Thomas E. Kehl, Florian |
author_sort | Gartmann, Thomas E. |
collection | PubMed |
description | Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide sensitivity for multiple film thicknesses, wavelengths and polarization of the propagating light. In this paper, the bulk refractive index sensitivity versus waveguide thickness of said refractometric sensors is experimentally determined and compared with predictions based on established theory. The effective refractive indices and the corresponding sensitivity were determined via the sensors’ coupling angles at different cover refractive indices for transverse electric as well as transverse magnetic polarized illumination at various wavelengths in the visible and near-infrared. The theoretical sensitivity was calculated by solving the mode equation for a three layer waveguide. |
format | Online Article Text |
id | pubmed-4493545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-44935452015-07-07 Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors Gartmann, Thomas E. Kehl, Florian Biosensors (Basel) Article Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide sensitivity for multiple film thicknesses, wavelengths and polarization of the propagating light. In this paper, the bulk refractive index sensitivity versus waveguide thickness of said refractometric sensors is experimentally determined and compared with predictions based on established theory. The effective refractive indices and the corresponding sensitivity were determined via the sensors’ coupling angles at different cover refractive indices for transverse electric as well as transverse magnetic polarized illumination at various wavelengths in the visible and near-infrared. The theoretical sensitivity was calculated by solving the mode equation for a three layer waveguide. MDPI 2015-04-13 /pmc/articles/PMC4493545/ /pubmed/25871832 http://dx.doi.org/10.3390/bios5020187 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gartmann, Thomas E. Kehl, Florian Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title | Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title_full | Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title_fullStr | Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title_full_unstemmed | Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title_short | Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors |
title_sort | experimental validation of the sensitivity of waveguide grating based refractometric (bio)sensors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493545/ https://www.ncbi.nlm.nih.gov/pubmed/25871832 http://dx.doi.org/10.3390/bios5020187 |
work_keys_str_mv | AT gartmannthomase experimentalvalidationofthesensitivityofwaveguidegratingbasedrefractometricbiosensors AT kehlflorian experimentalvalidationofthesensitivityofwaveguidegratingbasedrefractometricbiosensors |