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Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors

Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide...

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Detalles Bibliográficos
Autores principales: Gartmann, Thomas E., Kehl, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493545/
https://www.ncbi.nlm.nih.gov/pubmed/25871832
http://dx.doi.org/10.3390/bios5020187
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author Gartmann, Thomas E.
Kehl, Florian
author_facet Gartmann, Thomas E.
Kehl, Florian
author_sort Gartmann, Thomas E.
collection PubMed
description Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide sensitivity for multiple film thicknesses, wavelengths and polarization of the propagating light. In this paper, the bulk refractive index sensitivity versus waveguide thickness of said refractometric sensors is experimentally determined and compared with predictions based on established theory. The effective refractive indices and the corresponding sensitivity were determined via the sensors’ coupling angles at different cover refractive indices for transverse electric as well as transverse magnetic polarized illumination at various wavelengths in the visible and near-infrared. The theoretical sensitivity was calculated by solving the mode equation for a three layer waveguide.
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spelling pubmed-44935452015-07-07 Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors Gartmann, Thomas E. Kehl, Florian Biosensors (Basel) Article Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide sensitivity for multiple film thicknesses, wavelengths and polarization of the propagating light. In this paper, the bulk refractive index sensitivity versus waveguide thickness of said refractometric sensors is experimentally determined and compared with predictions based on established theory. The effective refractive indices and the corresponding sensitivity were determined via the sensors’ coupling angles at different cover refractive indices for transverse electric as well as transverse magnetic polarized illumination at various wavelengths in the visible and near-infrared. The theoretical sensitivity was calculated by solving the mode equation for a three layer waveguide. MDPI 2015-04-13 /pmc/articles/PMC4493545/ /pubmed/25871832 http://dx.doi.org/10.3390/bios5020187 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gartmann, Thomas E.
Kehl, Florian
Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title_full Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title_fullStr Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title_full_unstemmed Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title_short Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors
title_sort experimental validation of the sensitivity of waveguide grating based refractometric (bio)sensors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493545/
https://www.ncbi.nlm.nih.gov/pubmed/25871832
http://dx.doi.org/10.3390/bios5020187
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