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Revealing Three Stages of DNA-Cisplatin Reaction by a Solid-State Nanopore

The dynamic structural behavior in DNA due to interaction with cisplatin is essential for the functionality of platinum-based anti-cancer drugs. Here we report a novel method to monitor the interaction progress in DNA-cisplatin reaction in real time with a solid-state nanopore. The interaction proce...

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Detalles Bibliográficos
Autores principales:	Zhou, Zhi, Hu, Ying, Shan, Xinyan, Li, Wei, Bai, Xuedong, Wang, Pengye, Lu, Xinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493569/ https://www.ncbi.nlm.nih.gov/pubmed/26148968 http://dx.doi.org/10.1038/srep11868

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