Cargando…

BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors

Cilia harbor sensory receptors for various signaling cascades critical for vertebrate development. However, the mechanisms underlying the ciliary homeostasis of sensory receptors remain elusive. Here, we demonstrate that BBS-4 and BBS-5, two distinct BBSome components, show unexpected functional red...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Qingwen, Zhang, Yuxia, Wei, Qing, Huang, Yan, Li, Yan, Ling, Kun, Hu, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493597/
https://www.ncbi.nlm.nih.gov/pubmed/26150102
http://dx.doi.org/10.1038/srep11855

Ejemplares similares