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miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis

Multiple symmetric lipomatosis (MSL) is a rare disease characterized by symmetric and abnormal distribution of subcutaneous adipose tissue (SAT); however, the etiology is largely unknown. We report here that miR-125a-3p and miR-483-5p are upregulated in the SAT of MSL patients, promoting adipogenesi...

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Detalles Bibliográficos
Autores principales: Chen, Ke, He, Honghui, Xie, Yanhong, Zhao, Liling, Zhao, Shaoli, Wan, Xinxing, Yang, Wenjun, Mo, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493643/
https://www.ncbi.nlm.nih.gov/pubmed/26148871
http://dx.doi.org/10.1038/srep11909