Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1β secretion in response to anti-MPO antibodies

ANCA vasculitis encompasses several autoimmune conditions characterised by destruction of small vessels, inflammation of the respiratory tract and glomerulonephritis. Most patients harbour autoantibodies to myeloperoxidase (MPO) or proteinase 3 (PR3). Clinical and experimental data suggest that path...

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Detalles Bibliográficos
Autores principales: O’Brien, Eóin C., Abdulahad, Wayel H., Rutgers, Abraham, Huitema, Minke G., O’Reilly, Vincent P., Coughlan, Alice M., Harrington, Mark, Heeringa, Peter, Little, Mark A., Hickey, Fionnuala B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493694/
https://www.ncbi.nlm.nih.gov/pubmed/26149790
http://dx.doi.org/10.1038/srep11888

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