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Quantitative and qualitative analysis of the novel antitumor 1,3,4-oxadiazole derivative (GLB) and its metabolites using HPLC-UV and UPLC-QTOF-MS
Fructose-based 3-acetyl-2,3-dihydro-1,3,4-oxadiazole (GLB) is a novel antitumor agent and belongs to glycosylated spiro-heterocyclic oxadiazole scaffold derivative. This research first reported a simple, specific, sensitive and stable high performance liquid chromatography -ultraviolet detector (HPL...
Autores principales: | Li, Pu, Wang, Xin, Li, Jian, Meng, Zhi-Yun, Li, Shu-Chun, Li, Zhong-Jun, Lu, Ying-Yuan, Ren, Hong, Lou, Ya-Qing, Lu, Chuang, Dou, Gui-Fang, Zhang, Guo-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493701/ https://www.ncbi.nlm.nih.gov/pubmed/26148672 http://dx.doi.org/10.1038/srep11906 |
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