The genetic architecture of NAFLD among inbred strains of mice

To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet rich in fat and carbohydrates. A >30-fold...

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Detalles Bibliográficos
Autores principales: Hui, Simon T, Parks, Brian W, Org, Elin, Norheim, Frode, Che, Nam, Pan, Calvin, Castellani, Lawrence W, Charugundla, Sarada, Dirks, Darwin L, Psychogios, Nikolaos, Neuhaus, Isaac, Gerszten, Robert E, Kirchgessner, Todd, Gargalovic, Peter S, Lusis, Aldons J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493743/
https://www.ncbi.nlm.nih.gov/pubmed/26067236
http://dx.doi.org/10.7554/eLife.05607

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