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VISA - Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing
BACKGROUND: Analyzing the integration profile of retroviral vectors is a vital step in determining their potential genotoxic effects and developing safer vectors for therapeutic use. Identifying retroviral vector integration sites is also important for retroviral mutagenesis screens. RESULTS: We dev...
Autores principales: | Hocum, Jonah D., Battrell, Logan R., Maynard, Ryan, Adair, Jennifer E., Beard, Brian C., Rawlings, David J., Kiem, Hans-Peter, Miller, Daniel G., Trobridge, Grant D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493804/ https://www.ncbi.nlm.nih.gov/pubmed/26150117 http://dx.doi.org/10.1186/s12859-015-0653-6 |
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